Marc Sze

Post-doctoral Research Fellow since 2015

Research areas

  • Microbial ecology
  • Lung Bacterial Microbiome
  • Family Microbiome
  • Cancer
  • Obesity


  • BMLSc: University of British Columbia (2009)
  • MSc: University of British Columbia (2011)
  • PhD: University of British Columbia (2015)
Marc Sze


I previously spent a lot of time during my PhD investigating the lung bacterial microbiome and its role in the disease known as Chronic Obstructive Pulmonary Disease. I recently moved from the temperate westcoast to the University of Michigan. You might be asking, why? Well, I could not resist the opportunity to be mentored by Pat and to study the bacterial microbiome of families. My interests in the microbiome are mostly involved with how the human host interacts with the bacterial community, how this interaction could potentially cause or exacerbate disease, and how both these interactions contribute to helping to shape either the host cellular community or the bacterial microbiome.

Papers from time in Schloss lab

  1. Sze MA, Schloss PD. 2016. Looking for a Signal in the Noise: Revisiting Obesity and the Microbiome. mBio. 7: e01018-16. DOI: 10.1128/mBio.01018-16.
  2. Sze MA, Baxter NT, Ruffin MT IV, Rogers MAM, Schloss PD. 2017. Normalization of the microbiota in patients after treatment for colonic lesions. Microbiome. 5: 150. DOI: 10.1186/s40168-017-0366-3.
  3. Sze MA, Schloss PD. 2018. Leveraging Existing 16S rRNA Gene Surveys to Identify Reproducible Biomarkers in Individuals with Colorectal Tumors. mBio. 9: e00630-18. DOI: 10.1128/mBio.00630-18.
  4. Sze MA, Topçuoğlu BD, Lesniak NA, IV Ruffin MT, Schloss PD. 2019. Fecal short-chain fatty acids are not predictive of colonic tumor status and cannot be predicted based on bacterial community structure. mBio. 10: e01454-19. DOI: 10.1128/mBio.01454-19.
  5. Sze MA, Schloss PD. 2019. The impact of DNA polymerase and number of rounds of amplification in PCR on 16S rRNA gene sequence data. mSphere. 4: e00163-19. DOI: 10.1128/mSphere.00163-19.
  6. Hagan AK, Lesniak NA, Balunas MJ, Bishop L, Close WL, Doherty MD, Elmore AG, Flynn KJ, Hannigan GK, Koumpouras CC, Jenior ML, Kozik AJ, McBride K, Rifkin SB, Stough JMA, Sovacool KL, Sze MA, Tomkovich S, Topçuoğlu BD, Schloss PD. 2020. Ten simple rules to increase computational skills among biologists with Code Clubs. PLOS Computational Biology. 16: e1008119. DOI: 10.1371/journal.pcbi.1008119.
  7. Rifkin SB, Sze MA, Tuck K, Koeppe E, Stoffel EM, Schloss PD. 2023. Gut microbiome composition in Lynch Syndrome with and without history of colorectal neoplasia and non-Lynch controls. J Gastrointest Cancer. DOI: 10.1007/s12029-023-00925-4.