Colorectal cancer

  1. Armour CR, Sovacool KL, Close WL, Topcuoglu BD, Wiens J, Schloss PD. 2023. Machine learning classification by fitting amplicon sequences to existing OTUs. mSphere. 8: 00336-23. DOI: 10.1128/msphere.00336-23.
  2. Rifkin SB, Sze MA, Tuck K, Koeppe E, Stoffel EM, Schloss PD. 2023. Gut microbiome composition in Lynch Syndrome with and without history of colorectal neoplasia and non-Lynch controls. J Gastrointest Cancer. DOI: 10.1007/s12029-023-00925-4.
  3. Armour CR, Topcuoglu BD, Garretto A, Schloss PD. 2022. A Goldilocks Principle for the Gut Microbiome: Taxonomic Resolution Matters for Microbiome-Based Classification of Colorectal Cancer. mBio. 13: e03161-21. DOI: 10.1128/mbio.03161-21.
  4. Topçuoğlu BD, Lesniak NA, Ruffin MT IV, Wiens J, Schloss PD. 2020. Effective application of machine learning to microbiome-based classification problems. mBio. 11: 1-13. DOI: 10.1128/mBio.00434-20.
  5. Yu AI, Zhao L, Eaton KA, Ho S, Chen J, Poe S, Becker J, Gonzalez A, McKinstry D, Hasso M, Mendoza-Castrejon J, Whitfield J, Koumpouras C, Schloss PD, Martens EC, and Chen GY. 2020. Gut microbiota modulate CD8 T cell responses to influence colitis-associated tumorigenesis. Cell Reports. 31: 107471. DOI: 10.1016/j.celrep.2020.03.035.
  6. Sze MA, Topçuoğlu BD, Lesniak NA, IV Ruffin MT, Schloss PD. 2019. Fecal short-chain fatty acids are not predictive of colonic tumor status and cannot be predicted based on bacterial community structure. mBio. 10: e01454-19. DOI: 10.1128/mBio.01454-19.
  7. Flynn KJ, Ruffin MT IV, Turgeon DK, Schloss PD. 2018. Spatial variation of the native colon microbiota in healthy adults. Cancer Prev Res (Phila). 11: 393-401. DOI: 10.1158/1940-6207.CAPR-17-0370.
  8. Hannigan GD, Duhaime MB, Ruffin IV MT, Koumpouras CC, Schloss PD. 2018. The Diagnostic Potential and Interactive Dynamics of the Colorectal Cancer Virome. mBio. 9: e02248-18. DOI: 10.1128/mBio.02248-18.
  9. Sze MA, Schloss PD. 2018. Leveraging Existing 16S rRNA Gene Surveys to Identify Reproducible Biomarkers in Individuals with Colorectal Tumors. mBio. 9: e00630-18. DOI: 10.1128/mBio.00630-18.
  10. Seregin SS, Golovchenko N, Schaf B, Chen J, Pudlo NA, Mitchell J, Baxter NT, Zhao L, Schloss PD, Martens EC, Eaton KA, Chen GY. 2017. NLRP6 protects IL10-/- mice from colitis by limiting colonization of Akkermansia muciniphila. Cell Reports. 19: 733-745. DOI: 10.1016/j.celrep.2017.03.080.
  11. Sze MA, Baxter NT, Ruffin MT IV, Rogers MAM, Schloss PD. 2017. Normalization of the microbiota in patients after treatment for colonic lesions. Microbiome. 5: 150. DOI: 10.1186/s40168-017-0366-3.
  12. Baxter NT, Ruffin MT 4th, Rogers MA, Schloss PD. 2016. Microbiota-based model improves the sensitivity of fecal immunochemical test for detecting colonic lesions. Genome Medicine. 8: 1. DOI: 10.1186/s13073-016-0290-3.
  13. Baxter NT, Koumpouras CC, Rogers MA, Ruffin MT 4th, Schloss PD. 2016. DNA from fecal immunochemical test can replace stool for detection of colonic lesions using a microbiota-based model. Microbiome. 4: 59. DOI: 10.1186/s40168-016-0205-y.
  14. Flynn KJ, Baxter NT, Schloss PD. 2016. Metabolic and community synergy of oral bacteria in colorectal cancer. mSphere. 1: e00102-16. DOI: 10.1128/mSphere.00102-16.
  15. Zackular JP, Baxter NT, Chen GH, Schloss PD. 2015. Manipulation of the gut microbiota reveals role in colon tumorigenesis. mSphere. 1: e00001-e00015. DOI: 10.1128/mSphere.00001-15.
  16. Baxter NT, Zackular JP, Chen GY, Schloss PD. 2014. Structure of the gut microbiome following colonization with human feces determines colonic tumor burden. Microbiome. 2: 20. DOI: 10.1186/2049-2618-2-20.
  17. Zackular JP, Rogers MA, Ruffin MT 4th, Schloss PD. 2014. The human gut microbiome as a screening tool for colorectal cancer. Cancer Prev Res (Phila). 7: 1112-21. DOI: 10.1158/1940-6207.CAPR-14-0129.
  18. Zackular JP, Baxter NT, Iverson KD, Sadler WD, Petrosino JF, Chen GY, Schloss PD. 2013. The gut microbiome modulates colon tumorigenesis. mBio. 4: e00692-13. DOI: 10.1128/mBio.00692-13.

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