C. difficile Infection

  1. Barron MR, Sovacool KL, Abernathy-Close L, Vendrov KC, Standke AK, Bergin IL, Schloss PD, Young VB. 2022. Intestinal Inflammation Reversibly Alters the Microbiota to Drive Susceptibility to Clostridioides difficile Colonization in a Mouse Model of Colitis. mBio. 13: e0190422. DOI: 10.1128/mbio.01904-22.
  2. Lesniak NA, Schubert AM, Flynn KJ, Leslie JL, Sinani H, Bergin IL, Young VB, Schloss PD. 2022. The gut bacterial community potentiates Clostridioides difficile infection severity. mBio. DOI: 10.1128/mbio.01183-22.
  3. Lesniak NA, Tomkovich S, Henry A, Taylor A, Colovas J, Bishop L, McBride K, Schloss PD. 2022. Diluted fecal community transplant restores Clostridioides difficile colonization resistance to antibiotic perturbed murine communities. mBio. 13: e01364-22. DOI: 10.1128/mbio.01364-22.
  4. Leslie JL, Jenior ML, Vendrov KC, Standke AK, Barron MR, O’Brien TJ, Unverdorben L, Thaprawat P, Bergin IL, Schloss PD, Young VB. 2021. Protection from lethal Clostridioides difficile infection via intraspecies competition for co-germinant. mBio. 12: e00522-21. DOI: 10.1128/mBio.00522-21.
  5. Lesniak NA, Schubert AM, Sinani H, Schloss PD. 2021. Clearance of Clostridioides difficile colonization is associated with antibiotic-specific bacterial changes. mSphere. 6: e01238-20. DOI: 10.1128/mSphere.01238-20.
  6. Tomkovich S, Taylor A, King J, Colovas J, Bishop L, McBride K, Royzenblat S, Lesniak NA, Bergin IL, Schloss PD. 2021. An osmotic laxative renders mice susceptible to prolonged Clostridioides difficile colonization and hinders clearance. mSphere. 6: e00629-21. DOI: 10.1128/mSphere.00629-21.
  7. Stough JMA, Beaudoin AJ, Schloss PD. 2020. Coding-complete RNA virus genomes assembled from murine cecal metatranscriptomes. Microbiology Resource Announcements. 9: e00018-20. DOI: 10.1128/MRA.00018-20.
  8. Tomkovich S, Stough JMA, Bishop L, Schloss PD. 2020. The initial gut microbiota and response to antibiotic perturbation influence Clostridioides difficile colonization in mice. mSphere. 5: e00869-20. DOI: 10.1128/mSphere.00869-20.
  9. Maseda D, Zackular JP, Trindade B, Kirk L, Lising Roxas J, Rogers LM, Washington MK, Du L, Koyama T, Viswanathan VK, Vedantam G, Schloss PD, Crofford LJ, Skaar EP, Aronoff DM. 2019. Nonsteroidal anti-inflammatory drugs alter the microbiota and exacerbate Clostridium difficile colitis while dysregulating the inflammatory response. mBio. 10: e02282-18. DOI: 10.1128/mBio.02282-18.
  10. Tomkovich S, Lesniak NA, Li Y, Bishop L, Fitzgerald MG, Schloss PD. 2019. The proton pump inhibitor omeprazole does not promote Clostridium difficile colonization in a murine model. mSphere. 4: e00693-19. DOI: 10.1128/mSphere.00693-19.
  11. Jenior ML, Leslie JL, Young VB, Schloss PD. 2018. Clostridium difficile differentially alters the structure and metabolism of distinct cecal microbiomes to promote persistent colonization during infection. mSphere. 3: e00261-18. DOI: 10.1128/mSphere.00261-18.
  12. Jenior ML, Leslie JL, Young VB, Schloss PD. 2017. Clostridium difficile colonizes alternative nutrient niches during infection across distinct murine gut environments. mSystems. 2: e00063-17. DOI: 10.1128/mSystems.00063-17.
  13. Koenigsknecht MJ, Theriot CM, Bergin IL, Schumacher CA, Schloss PD, Young VB. 2015. Dynamics and establishment of Clostridium difficile infection in the murine gastrointestinal tract. Infect Immun. 83: 934-41. DOI: 10.1128/IAI.02768-14.
  14. Kopliku FA, Schubert AM, Mogle J, Schloss PD, Young VB, Aronoff DM. 2015. Low prevalence of Clostridium septicum fecal carriage in an adult population. Anaerobe. 32: 34-6. DOI: 10.1016/j.anaerobe.2014.12.001.
  15. Schubert AM, Sinani H, Schloss PD. 2015. Antibiotic-induced alterations of the murine gut microbiota and subsequent effects on colonization resistance against Clostridium difficile. mBio. 6: e00974-15. DOI: 10.1128/mBio.00974-15.
  16. Schubert AM, Rogers MA, Ring C, Mogle J, Petrosino JP, Young VB, Aronoff DM, Schloss PD. 2014. Microbiome data distinguish patients with Clostridium difficile infection and non-C. difficile-associated diarrhea from healthy controls. mBio. 5: e01021-14. DOI: 10.1128/mBio.01021-14.
  17. Reeves AE, Theriot CM, Bergin IL, Huffnagle GB, Schloss PD, Young VB. 2011. The interplay between microbiome dynamics and pathogen dynamics in a murine model of Clostridium difficile infection. Gut Microbes. 2: 145-58. DOI: 10.4161/gmic.2.3.16333.

back…